Presentazione:

BIOLOGIST
SC Servizio di Medicina di Laboratorio - Genetica Medica e Neurogenetica
(italian version)

 

I graduated in Biology at the University of Naples “Federico II” in 2007 and I obtained my PhD in Translational and Molecular Medicine at the University of Milan “Bicocca” in 2012. In 2023 I completed the school of specialization in Medical Genetics at the University of Milan.

 

Research activities

My research interest has mainly focused on understanding the pathogenesis of mitochondrial and neurodegenerative genetic rare diseases and on the use of preclinical models to develop potential new therapeutic approaches using both pharmacological and gene therapy strategies.

From 2013 to 2014 I carried out postdoctoral research activity at the Mitochondrial Biology Unit (MBU), University of Cambridge (UK), where I refined my expertise on basic and translational research related to rare genetic diseases with mitochondrial involvement. Back in Italy, besides continuing my research in the field of mitochondrial medicine, I expanded my scientific interests focusing on the study of the molecular mechanisms underlying neurodegenerations with brain iron accumulation (NBIA) caused by inborn errors of Coenzyme A metabolism.

Since 2019, thanks to a Young Researcher Grant funded by the Italian Ministry of Health, I coordinate a small group involved in the generation and characterization of cellular and animal models, with the ultimate goals of identifying the mechanisms underlying the pathogenesis of rare mitochondrial and neurodegenerative diseases, as well as developing innovative and personalized therapeutic approaches.

 

Topics of interest

• Mitochondrial medicine
• Mitochondrial neurodegenerative diseases
• In vitro and in vivo models of genetic diseases

 

Contacts

+39 02.2394.2625

email: ivano.dimeo@istituto-besta.it