The IRCCS Foundation “Carlo Besta” Neurological Institute, of national importance, is based on the statute of a participating Foundation, represented by a Board of Directors; which consists of members of the Region of Lombardy, the Italian Ministry of Health and the City of Milan which have specific representation on the Board of Directors. In June 2009 an agreement was stipulated which allowed the Mariani Foundation the first private entity to participate alongside the public founders. The governing bodies of the Foundation are: the President, the Board of Directors, the General Manager, the Scientific Director and the Board of Statutory Auditors. In the regional and national health framework, the IRCCS Foundation “Carlo Besta” Neurological Institute is a center of excellence for research and treatment of the most important neurological diseases. It synergistically combines the activities of scientific research, diagnosis and treatment - which gives rise to a continuous improvement of therapeutic efficacy - in the field of clinical and basic neurology and deals with neurological disorders in adults and children, neurosurgical and oncological pathologies, chronic and rare diseases.