Presentazione:

PHARMACEUTICAL CHEMIST AND TECHNOLOGIST
SC  Neurologia 7 - Epilettologia Clinica e Sperimentale
(italian version)

 

Since my graduation in Pharmaceutical Chemistry and Technology from the University of Milan, my research interests have involved the development of a comprehensive understanding of key pathways and alterations in neurological diseases. As PhD student, my research focused on the molecular mechanisms underlying neuroprotection in in-vitro models of neuronal apoptosis. I held Post-Doc positions in the Institute of Biochemistry at ETH Zurich and in the Department of Medical Biotechnology and Translational Medicine, University of Milan, working on communication between neuronal and non-neuronal cells in the central nervous system (CNS), secretory pathways in non-neuronal CNS cells and their involvement in neuropathology. My work shifted to highly translational projects in Fondazione Filarete for Bioscience and Innovation, Milan. 

 

Research activity

In 2016 I joined the Fondazione IRCCS Istituto Neurologico Carlo Besta, where I am in charge of the basic research projects studying the pathogenetic mechanisms of Spinal Muscular Atrophy (SMA). SMA is a severe genetic disease, which leads to motor neuron degeneration. My studies are focused on the role of SMN, the protein responsible for the disease, in development and differentiation of CNS cells, with an in-vivo and in-vitro approach.

I am also referent for the MALDI imaging mass spectrometry platform and working on a project aimed at studying MALDI imaging as a tool to improve diagnosis in patients undergoing surgery for drug resistant focal epilepsy.

 

 

Topics of interest

• SMA (Muscular Spinal Atrophy)
• Neurodegeneration
• MALDI Imaging

 

 

Contacts

+39 02.2394.4522

email: cinzia.cagnoli@istituto-besta.it